Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 13/20 | 0.69 |
| ▸ | PFKFB4 | Q16877 | 8/20 | 0.62 |
| ▸ | CMA1 | P23946 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL788416 | 0.85 | PFKFB3 (0.68) | PFKFB3PFKFB4CMA1 | |
| SCHEMBL787910 | 0.82 | PFKFB3 (1.00) | PFKFB3PFKFB4 | |
| SCHEMBL788169 | 0.76 | PFKFB3 (1.00) | PFKFB3PFKFB4 | |
| SCHEMBL28652870 | 0.74 | PFKFB3 (0.71) | PFKFB3PFKFB4CMA1 | |
| SCHEMBL788563 | 0.74 | PFKFB3 (1.00) | PFKFB3PFKFB4 | |
| SCHEMBL9997094 | 0.73 | PFKFB3 (0.71) | PFKFB3PFKFB4CMA1 | |
| SCHEMBL787888 | 0.73 | PFKFB3 (1.00) | PFKFB3PFKFB4CMA1 | |
| SCHEMBL793880 | 0.73 | PFKFB3 (1.00) | PFKFB3PFKFB4 | |
| SCHEMBL793936 | 0.73 | PFKFB4 (1.00) | PFKFB3PFKFB4CMA1 | |
| SCHEMBL793735 | 0.73 | PFKFB3 (0.75) | PFKFB3PFKFB4CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616450-A2 | SULFONAMIDE COMPOUNDS | Kancera AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035171-A2 | NEW COMPOUNDS | KANCERA AB (SE) | 2012-03-22 | — | — | WO | disclosed |