SCHEMBL7882117

SCHEMBL7882117

CCOC(=O)[C@H](Cc1ccccc1)NC=O

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.55
HPRT1 P00492 1/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
TAAR1 Q96RJ0 1/20 0.53
TP53 P04637 2/20 0.52
EPHX1 P07099 1/20 0.51
ELANE P08246 1/20 0.50
ALDH1A1 P00352 2/20 0.48
TACR1 P25103 1/20 0.48
EGFR P00533 1/20 0.47
POLB P06746 2/20 0.47
DAGLA Q9Y4D2 1/20 0.47
EPHX2 P34913 1/20 0.46
PPARG P37231 1/20 0.46
GAA P10253 1/20 0.46
RAB9A P51151 1/20 0.46
ATM Q13315 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6952367 1.00 MMP8 (0.55) MMP8HPRT1MEN1KMT2ATAAR1
SCHEMBL6952364 0.88 MEN1 (0.50) MMP8HPRT1MEN1KMT2ATAAR1
SCHEMBL1274700 0.88 ATM (0.58) MEN1KMT2ATAAR1EPHX1ALDH1A1
SCHEMBL3499885 0.88 ATM (0.58) MEN1KMT2ATAAR1EPHX1ALDH1A1
SCHEMBL27925079 0.88 ATM (0.58) MEN1KMT2ATAAR1EPHX1ALDH1A1
SCHEMBL10885963 0.86 EPHX1 (0.53) MEN1KMT2ATAAR1EPHX1ALDH1A1
SCHEMBL11769408 0.86 TP53 (0.49) MMP8HPRT1TP53ALDH1A1TACR1
SCHEMBL6946568 0.86 DAGLA (0.51) HPRT1MEN1KMT2ATAAR1EPHX1
SCHEMBL6952487 0.85 MEN1 (0.54) MEN1KMT2ATAAR1EPHX1ALDH1A1
SCHEMBL4538023 0.85 HDAC1 (0.45) MMP8HPRT1MEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6333427-B1 EXTRACTING OPTICALLY ACTIVE FORM OF N-T-BUTOXYCARBONYLPHENYLALANINE ESTER IN CRUDE PREPARATION INTO ALIPHATIC HYDROCARBON, RECOVERING ESTER PREPARATION HAVING IMPROVED OPTICAL PURITY MITSUI CHEMICALS, INC. (JP) 2001-12-25 US disclosed
EP-1031560-A1 Process for preparing N-t-butoxycarbonylphenylalanine ester Mitsui Chemicals, Inc. (JP) 2000-08-30 EP disclosed