Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 18/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7883941 | 0.88 | MTOR (0.50) | MTORCCNE1CDK2ALOX5APFEN1 | |
| SCHEMBL7880600 | 0.87 | MTOR (0.54) | MTOR | |
| SCHEMBL7872340 | 0.86 | MTOR (0.55) | MTORCCNE1CDK2 | |
| SCHEMBL696297 | 0.83 | MTOR (0.74) | MTORCCNE1CDK2 | |
| SCHEMBL12137747 | 0.83 | MTOR (0.46) | MTORALOX5APFEN1 | |
| SCHEMBL12774593 | 0.82 | MTOR (0.73) | MTOR | |
| SCHEMBL6890802 | 0.81 | PIK3CA (0.56) | MTOR | |
| SCHEMBL12773647 | 0.81 | MTOR (0.71) | MTORCCNE1CDK2 | |
| SCHEMBL7877513 | 0.80 | GABRP (0.51) | MTOR | |
| SCHEMBL12773418 | 0.80 | MTOR (0.75) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122069-A1 | 5-ALKYNYL-PYRIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-10-28 | — | — | WO | disclosed |