⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557065 | 1.00 | — | — | |
| SCHEMBL7883171 | 1.00 | — | — | |
| SCHEMBL7890622 | 0.86 | GPR119 (0.32) | — | |
| SCHEMBL7890624 | 0.86 | GPR119 (0.32) | — | |
| SCHEMBL7893540 | 0.85 | IDO1 (0.32) | — | |
| SCHEMBL7890544 | 0.85 | IDO1 (0.33) | — | |
| SCHEMBL7890541 | 0.85 | IDO1 (0.33) | — | |
| SCHEMBL7893537 | 0.85 | IDO1 (0.32) | — | |
| SCHEMBL7893523 | 0.84 | — | — | |
| SCHEMBL7893520 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180622-B1 | ANTIMICROBIAL ACTIVITY AGAINST A WIDE RANGE OF BACTERIA INCLUDING GRAM-POSITIVE BACTERIA, GRAM-NEGATIVE BACTERIA, BETA-LACTAMASE-PRODUCING BACTERIA, RESISTANT PSEUDOMONAS AERUGINOSA,METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AND | MEIJI SEIKA KAISHA, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0887352-A1 | CARBAPENEM DERIVATIVES AND ANTIMICROBIALS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-12-30 | — | — | EP | disclosed |