Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.56 |
| ▸ | SHBG | P04278 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37618 | 0.90 | CYP3A4 (0.70) | CYP19A1CYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7875309 | 0.88 | CYP19A1 (0.61) | CYP19A1CYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7875311 | 0.88 | CYP19A1 (0.61) | CYP19A1CYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11754343 | 0.83 | CYP3A4 (0.69) | CYP19A1CYP3A4LMNAMAPTMAPK1 | |
| SCHEMBL2600423 | 0.83 | CYP3A4 (0.69) | CYP19A1CYP3A4LMNAMAPTMAPK1 | |
| SCHEMBL11754338 | 0.83 | CYP3A4 (0.69) | CYP19A1CYP3A4LMNAMAPTMAPK1 | |
| SCHEMBL13845093 | 0.83 | CYP3A4 (0.81) | CYP19A1CYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL18708949 | 0.83 | CYP3A4 (0.81) | CYP19A1CYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7520546 | 0.82 | CYP19A1 (0.68) | CYP19A1CYP3A4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7884266 | 0.82 | CYP19A1 (0.68) | CYP19A1CYP3A4ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331534-B1 | ADMINISTERING EFFECTIVE AMOUNT OF STEROID WITHIN NASAL PASSAGE OF INDIVIDUAL SUCH THAT IT BINDS SPECIFICALLY TO RECEPTORS ON SURFACE OF NASAL NEUROEPITHELIAL CELLS IN VOMERONASAL ORGAN | PHERIN PHARMACEUTICALS, INC. | 2001-12-18 | — | — | US | disclosed |
| US-6117860-A | NASALLY ADMINISTERING STEROID WHICH BINDS TO A SPECIFIC NEUROEPITHELIAL RECEPTOR FOR ALLEVIATING PREMENSTRUAL TENSION AND ANXIETY | PHERIN PHARMACEUTICALS, INC. (US) | 2000-09-12 | — | — | US | disclosed |
| US-6066627-A | ALTERING BLOOD CONCNETRATION OF LUTEINIZING HORMONE | PHERIN CORPORATION (US) | 2000-05-23 | — | — | US | disclosed |
| US-6057439-A | EPOXYSTEROIDS | PHERIN CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |
| US-5994333-A | NASAL ADMINISTERING | PHERIN CORPORATION (US) | 1999-11-30 | — | — | US | disclosed |