SCHEMBL37618

SCHEMBL37618

CC(=O)[C@H]1CC[C@H]2[C@@H]3CC(=O)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.70
ALDH1A1 P00352 5/20 0.70
SMN1; SMN2 Q16637 5/20 0.70
SERPINA6 P08185 5/20 0.70
LMNA P02545 3/20 0.70
MAPT P10636 3/20 0.70
MAPK1 P28482 3/20 0.70
CYP2C9 P11712 2/20 0.70
TSHR P16473 2/20 0.70
HIF1A Q16665 2/20 0.70
CYP2C19 P33261 2/20 0.70
PGR P06401 2/20 0.70
AR P10275 2/20 0.70
CHRM1 P11229 2/20 0.70
ADRA1A P35348 2/20 0.70
ABCB11 O95342 2/20 0.70
SHBG P04278 2/20 0.70
NR3C2 P08235 2/20 0.70
KDM4E B2RXH2 1/20 0.70
MEN1 O00255 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7884191 0.90 CYP19A1 (0.61) CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA
SCHEMBL7875309 0.89 CYP19A1 (0.61) CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA
SCHEMBL13981790 0.89 CYP3A4 (0.67) CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA
SCHEMBL1444719 0.89 CYP3A4 (0.67) CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA
SCHEMBL7875311 0.89 CYP19A1 (0.61) CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA
SCHEMBL367638 0.89 CYP3A4 (0.67) CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA
SCHEMBL2600423 0.84 CYP3A4 (0.69) CYP3A4SERPINA6LMNAMAPTMAPK1
SCHEMBL11754343 0.84 CYP3A4 (0.69) CYP3A4SERPINA6LMNAMAPTMAPK1
SCHEMBL11754338 0.84 CYP3A4 (0.69) CYP3A4SERPINA6LMNAMAPTMAPK1
SCHEMBL10926290 0.83 ALDH1A1 (0.60) CYP3A4ALDH1A1SMN1; SMN2SERPINA6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117030904-B Method for measuring 144 steroid hormones in environmental sample by liquid chromatography-mass spectrometry 北京林业大学 2023-12-19 CN claimed
CN-117030904-A Method for measuring 144 steroid hormones in environmental sample by liquid chromatography-mass spectrometry 北京林业大学 2023-11-10 CN claimed
US-9572818-B2 Pharmaceutical emulsion compositions comprising progestogen BESINS HEALTHCARE LUXEMBOURG SARL (LU) 2017-02-21 US disclosed
EP-2857042-B1 Low-oil pharmaceutical emulsion compositions comprising progestogen BESINS HEALTHCARE LU SARL (LU) 2016-08-31 EP disclosed
CN-102946865-B Comprise the pharmaceutical emulsion composition of the low oil of progestogen 博赏医药卢森堡责任有限公司 2016-06-22 CN disclosed
EP-2801353-B1 Pharmaceutical Emulsion Compositions Comprising Progestogen BESINS HEALTHCARE LU SARL (LU) 2016-03-30 EP disclosed
EP-2857042-A1 Low-oil pharmaceutical emulsion compositions comprising progestogen Besins Healthcare Luxembourg (LU) 2015-04-08 EP disclosed
EP-2563335-B1 LOW-OIL PHARMACEUTICAL EMULSION COMPOSITIONS COMPRISING PROGESTOGEN BESINS HEALTHCARE LU SARL (LU) 2014-12-17 EP disclosed
US-20140335133-A1 LOW-OIL PHARMACEUTICAL EMULSION COMPOSITIONS COMPRISING PROGESTOGEN BESINS HEALTHCARE LUXEMBOURG SARL (LU) 2014-11-13 US disclosed
EP-2801353-A1 Pharmaceutical Emulsion Compositions Comprising Progestogen Besins Healthcare Luxembourg (LU) 2014-11-12 EP disclosed
US-8765149-B2 Low-oil pharmaceutical emulsion compositions comprising progestogen BESINS HEALTHCARE LUXEMBOURG SARL (LU) 2014-07-01 US disclosed
EP-2563334-A2 PHARMACEUTICAL EMULSION COMPOSITIONS COMPRISING PROGESTOGEN Besins Healthcare Luxembourg SARL (LU) 2013-03-06 EP disclosed
CN-102946865-A Low-oil pharmaceutical emulsion compositions comprising progestogen BESINS HEALTHCARE LU SARL 2013-02-27 CN disclosed
CN-102946864-A Pharmaceutical emulsion compositions comprising progestogen BESINS HEALTHCARE LU SARL 2013-02-27 CN disclosed
WO-2011134937-A2 PHARMACEUTICAL EMULSION COMPOSITIONS COMPRISING PROGESTOGEN BESINS HEALTHCARE LUXEMBOURG SARL (LU) 2011-11-03 WO disclosed
WO-2011134944-A2 LOW-OIL PHARMACEUTICAL EMULSION COMPOSITIONS COMPRISING PROGESTOGEN BESINS HEALTHCARE LUXEMBOURG SARL (LU) 2011-11-03 WO disclosed
US-20110262494-A1 LOW-OIL PHARMACEUTICAL EMULSION COMPOSITIONS COMPRISING PROGESTOGEN BESINS HEALTHCARE LUXEMBOURG SARL 2011-10-27 US disclosed
US-20110262495-A1 PHARMACEUTICAL EMULSION COMPOSITIONS COMPRISING PROGESTOGEN BESINS HEALTHCARE LUXEMBOURG SARL 2011-10-27 US disclosed
US-4201778-A 6-Acyloxy-1,4,6-pregnatrienes, their use as anti-inflammatory agents, methods for their manufacture, and 6-oxo-1,4-pregnadiene intermediates SCHERING CORPORATION (US) 1980-05-06 US disclosed
US-4201778-A 6-Acyloxy-1,4,6-pregnatrienes, their use as anti-inflammatory agents, methods for their manufacture, and 6-oxo-1,4-pregnadiene intermediates SCHERING CORPORATION (US) 1980-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110262495-A1 PHARMACEUTICAL EMULSION COMPOSITIONS COMPRISING PROGESTOGEN PGR, CYP17A1, CYP19A1 CYP3A4 287/4885ALDH1A1 4514/4885SMN1; SMN2 1331/4885
US-20140335133-A1 LOW-OIL PHARMACEUTICAL EMULSION COMPOSITIONS COMPRISING PROGESTOGEN PGR, CYP17A1, PGRMC1 CYP3A4 696/4885ALDH1A1 4653/4885SMN1; SMN2 1249/4885
US-20110262494-A1 LOW-OIL PHARMACEUTICAL EMULSION COMPOSITIONS COMPRISING PROGESTOGEN PGR, CYP17A1, PGRMC1 CYP3A4 696/4885ALDH1A1 4653/4885SMN1; SMN2 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.