Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | LHCGR | P22888 | 11/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171476 | 0.91 | LHCGR (0.57) | POLBLHCGRNPSR1L3MBTL1 | |
| SCHEMBL7889844 | 0.87 | LHCGR (0.69) | POLBLHCGRCNR1NPSR1 | |
| SCHEMBL7887385 | 0.85 | POLB (0.63) | POLBLHCGRCNR1NPSR1L3MBTL1 | |
| SCHEMBL7880270 | 0.83 | POLB (0.58) | POLBLHCGRCNR1NPSR1L3MBTL1 | |
| SCHEMBL8172061 | 0.82 | LHCGR (0.47) | POLBLHCGRNPSR1L3MBTL1 | |
| SCHEMBL7880373 | 0.81 | POLB (0.58) | POLBLHCGRCNR1 | |
| SCHEMBL7880247 | 0.80 | NPSR1 (0.49) | POLBLHCGRNPSR1L3MBTL1 | |
| SCHEMBL7888237 | 0.78 | MAPK1 (0.67) | LHCGRNPSR1 | |
| SCHEMBL7880184 | 0.78 | MEN1 (0.56) | POLBLHCGRNPSR1L3MBTL1 | |
| SCHEMBL7887769 | 0.78 | POLB (0.52) | POLBLHCGRNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177443-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-01-23 | — | — | US | disclosed |
| EP-0973778-A1 | 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040385-A1 | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-09-17 | — | — | WO | disclosed |