Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | LHCGR | P22888 | 12/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HHAT | Q5VTY9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887722 | 0.85 | MAPK1 (0.72) | NPSR1MAPK1LHCGRHHAT | |
| SCHEMBL7891856 | 0.85 | POLB (0.64) | LHCGRHHAT | |
| SCHEMBL7885900 | 0.85 | LHCGR (0.71) | NPSR1MAPK1LHCGRHHAT | |
| SCHEMBL7885827 | 0.82 | LHCGR (0.67) | NPSR1MAPK1LHCGRHHAT | |
| SCHEMBL7887404 | 0.81 | MAPK1 (0.66) | NPSR1MAPK1LHCGRHHAT | |
| SCHEMBL7880479 | 0.81 | LHCGR (0.64) | NPSR1MAPK1LHCGRHHAT | |
| SCHEMBL7888302 | 0.81 | MAPK1 (0.65) | NPSR1MAPK1LHCGRHHAT | |
| SCHEMBL8163727 | 0.80 | LHCGR (0.66) | NPSR1MAPK1LHCGR | |
| SCHEMBL8496340 | 0.79 | MAPK1 (0.54) | NPSR1MAPK1LHCGRHHAT | |
| SCHEMBL7889696 | 0.78 | HHAT (0.63) | NPSR1MAPK1LHCGRHHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177443-B1 | ANTIDIABETIC AGENTS | NOVO NORDISK A/S (DK) | 2001-01-23 | — | — | US | claimed |
| EP-0973778-A1 | 4,5,6,7-TETRAHYDRO-THIENO 3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-01-26 | — | — | EP | claimed |
| WO-1998040385-A1 | 4,5,6,7-TETRAHYDRO-THIENO[3,2-c]PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-09-17 | — | — | WO | claimed |