SCHEMBL788912

SCHEMBL788912

[CH2]c1c[nH]c2cccc(OC)c12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.55
HTR2B P41595 2/20 0.53
HTR6 P50406 2/20 0.53
HTR2C P28335 1/20 0.53
HTR1A P08908 1/20 0.47
HTR7 P34969 1/20 0.47
HTR5A P47898 1/20 0.47
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
MMP9 P14780 1/20 0.45
ABCG2 Q9UNQ0 1/20 0.42
KIF20A O95235 1/20 0.41
CLK1 P49759 1/20 0.41
DYRK1A Q13627 1/20 0.41
DRD2 P14416 3/20 0.38
DRD3 P35462 3/20 0.38
DRD4 P21917 2/20 0.38
ABL1 P00519 1/20 0.38
RAD52 P43351 1/20 0.38
RIN1 Q13671 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28167758 0.82 HTR2A (0.60) HTR2AHTR2BHTR6HTR2CHTR1A
SCHEMBL788913 0.79 HTR2A (0.57) HTR2AHTR2BHTR6HTR2CHTR1A
SCHEMBL24189182 0.78 HTR2A (0.59) HTR2AHTR2BHTR6HTR2CHTR1A
SCHEMBL21623873 0.78 HTR2A (0.55) HTR2AHTR2BHTR6HTR2CHTR1A
SCHEMBL25990078 0.78 HTR2A (0.59) HTR2AHTR2BHTR6HTR2CHTR1A
SCHEMBL24723620 0.78 HTR2A (0.55) HTR2AHTR2BHTR6HTR2CHTR1A
SCHEMBL29992709 0.78 HTR2A (0.55) HTR2AHTR2BHTR6HTR2CHTR1A
SCHEMBL13302230 0.78 HTR2A (0.55) HTR2AHTR2BHTR6HTR2CHTR1A
SCHEMBL26264188 0.78 HTR2A (0.55) HTR2AHTR2BHTR6HTR2CHTR1A
SCHEMBL16437208 0.75 HTR2A (0.69) HTR2AHTR2BHTR6HTR2CHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114324723-A Qualitative detection method for radish glucosinolates 湖北省农业科学院经济作物研究所 2022-04-12 CN claimed
CN-111601896-A Brassicaceae products containing isothiocyanates and methods of making the same 联邦科学技术研究组织 2020-08-28 CN claimed
US-20200255872-A1 Isothiocyanate containing Brassicaceae Products and Method of Preparation Thereof COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2020-08-13 US claimed
EP-3688179-A1 ISOTHIOCYANATE CONTAINING BRASSICACEAE Commonwealth Scientific and Industrial Research Organisation (AU) 2020-08-05 EP claimed
CN-111297931-A Broccoli total effective part extract and preparation method and application thereof 成都市三禾田生物技术有限公司 2020-06-19 CN claimed
WO-2019060963-A1 ISOTHIOCYANATE CONTAINING BRASSICACEAE PRODUCTS AND METHOD OF PREPARATION THEREOF COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2019-04-04 WO claimed
US-20160331725-A1 USE OF COMPOUNDS THAT ARE ABLE TO INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASE STATES ASSOCIATED WITH A REDUCED IGF-1 SERUM LEVEL IN HUMANS AND ANIMALS VEIJLEN N.V. 2016-11-17 US claimed
JP-4641942-B2 2011-03-02 JP claimed
US-20090326056-A1 NOVEL ACTIVES AGAINST PROSTATE CARCINOMA DSM IP ASSETS B.V. (NL) 2009-12-31 US claimed
EP-1569628-B1 NOVEL USE OF LYCOPENE FOR THE TREATMENT OF DISEASES ASSOCIATED WITH ANDROGEN SIGNALLING DSM IP ASSETS BV (NL) 2009-07-22 EP claimed
US-20080194553-A1 compounds that are capable of increasing the serum level of insulin-like growth factor 1 (IGF-1) for the preparation of a therapeutical composition,in the form of a food supplement, for the treatment of subjects suffering from serious fatigue and exhausting symptoms, burn-out and chronic fatigue syndrome VEIJLEN N.V. (NL) 2008-08-14 US claimed
WO-2007131767-A2 NOVEL ACTIVES AGAINST PROSTATE CARCINOMA DSM IP ASSETS B.V. (NL) 2007-11-22 WO claimed
EP-1670444-A2 USE OF INDOLEACETIC ACID DERIVATIVES WHICH INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASES Veijlen N.V. (AN) 2006-06-21 EP claimed
US-20060069151-A1 Novel use of lycopene DSM IP ASSETS B.V. (NL) 2006-03-30 US claimed
US-20060020046-A1 Compositions comprising lycopene for the treatment and prevention of angiogenesis associated pathologies DMS IP ASSETS B.V. (NL) 2006-01-26 US claimed
EP-1569628-A1 NOVEL USE OF LYCOPENE DSM IP Assets B.V. (NL) 2005-09-07 EP claimed
WO-2005039546-A2 USE OF INDOLEACETIC ACID DERIVATIVES WHICH INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASES VEIJLEN N.V. (AN) 2005-05-06 WO claimed
EP-1476143-A1 COMPOSITIONS COMPRISING LYCOPENE FOR THE TREATMENT AND PREVENTION OF ANGIOGENESIS ASSOCIATED PATHOLOGIES DSM IP Assets B.V. (NL) 2004-11-17 EP claimed
WO-2004052351-A1 NOVEL USE OF LYCOPENE DSM IP ASSETS B.V. (CH) 2004-06-24 WO claimed
WO-2003068202-A1 COMPOSITIONS COMPRISING LYCOPENE FOR THE TREATMENT AND PREVENTION OF ANGIOGENESIS ASSOCIATED PATHOLOGIES DSM IP ASSETS B.V. (NL) 2003-08-21 WO claimed