SCHEMBL788913

SCHEMBL788913

COc1cccc2[nH]cc(C)c12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 5/20 0.57
HTR2B P41595 2/20 0.54
HTR2C P28335 2/20 0.54
HTR6 P50406 2/20 0.54
HTR1A P08908 1/20 0.48
HTR7 P34969 1/20 0.48
HTR5A P47898 1/20 0.48
MTNR1A P48039 1/20 0.48
MTNR1B P49286 1/20 0.48
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
GPR84 Q9NQS5 1/20 0.46
MMP9 P14780 1/20 0.46
ATM Q13315 1/20 0.44
ABCG2 Q9UNQ0 1/20 0.44
KIF20A O95235 1/20 0.42
CLK1 P49759 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959984 0.85 GPR84 (0.55) HTR2AHTR2BHTR2CHTR6HTR1A
SCHEMBL28167758 0.84 HTR2A (0.60) HTR2AHTR2BHTR2CHTR6HTR1A
SCHEMBL29992709 0.79 HTR2A (0.55) HTR2AHTR2BHTR2CHTR6HTR1A
SCHEMBL21623873 0.79 HTR2A (0.55) HTR2AHTR2BHTR2CHTR6HTR1A
SCHEMBL26264188 0.79 HTR2A (0.55) HTR2AHTR2BHTR2CHTR6HTR1A
SCHEMBL24723620 0.79 HTR2A (0.55) HTR2AHTR2BHTR2CHTR6HTR1A
SCHEMBL24189182 0.79 HTR2A (0.59) HTR2AHTR2BHTR2CHTR6HTR1A
SCHEMBL788912 0.79 HTR2A (0.55) HTR2AHTR2BHTR2CHTR6HTR1A
SCHEMBL13302230 0.79 HTR2A (0.55) HTR2AHTR2BHTR2CHTR6HTR1A
SCHEMBL25990078 0.79 HTR2A (0.59) HTR2AHTR2BHTR2CHTR6HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114324723-A Qualitative detection method for radish glucosinolates 湖北省农业科学院经济作物研究所 2022-04-12 CN claimed
CN-111601896-A Brassicaceae products containing isothiocyanates and methods of making the same 联邦科学技术研究组织 2020-08-28 CN claimed
CN-111297931-A Broccoli total effective part extract and preparation method and application thereof 成都市三禾田生物技术有限公司 2020-06-19 CN claimed
US-20160331725-A1 USE OF COMPOUNDS THAT ARE ABLE TO INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASE STATES ASSOCIATED WITH A REDUCED IGF-1 SERUM LEVEL IN HUMANS AND ANIMALS VEIJLEN N.V. 2016-11-17 US claimed
JP-4641942-B2 2011-03-02 JP claimed
US-20090326056-A1 NOVEL ACTIVES AGAINST PROSTATE CARCINOMA DSM IP ASSETS B.V. (NL) 2009-12-31 US claimed
EP-1569628-B1 NOVEL USE OF LYCOPENE FOR THE TREATMENT OF DISEASES ASSOCIATED WITH ANDROGEN SIGNALLING DSM IP ASSETS BV (NL) 2009-07-22 EP claimed
EP-2020997-A2 NOVEL ACTIVES AGAINST PROSTATE CARCINOMA DSMIP Assets B.V. (NL) 2009-02-11 EP claimed
US-20080194553-A1 compounds that are capable of increasing the serum level of insulin-like growth factor 1 (IGF-1) for the preparation of a therapeutical composition,in the form of a food supplement, for the treatment of subjects suffering from serious fatigue and exhausting symptoms, burn-out and chronic fatigue syndrome VEIJLEN N.V. (NL) 2008-08-14 US claimed
WO-2007131767-A2 NOVEL ACTIVES AGAINST PROSTATE CARCINOMA DSM IP ASSETS B.V. (NL) 2007-11-22 WO claimed
EP-1670444-A2 USE OF INDOLEACETIC ACID DERIVATIVES WHICH INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASES Veijlen N.V. (AN) 2006-06-21 EP claimed
US-20060069151-A1 Novel use of lycopene DSM IP ASSETS B.V. (NL) 2006-03-30 US claimed
US-20060020046-A1 Compositions comprising lycopene for the treatment and prevention of angiogenesis associated pathologies DMS IP ASSETS B.V. (NL) 2006-01-26 US claimed
EP-1569628-A1 NOVEL USE OF LYCOPENE DSM IP Assets B.V. (NL) 2005-09-07 EP claimed
WO-2005039546-A2 USE OF INDOLEACETIC ACID DERIVATIVES WHICH INCREASE THE SERUM IGF-1 LEVEL FOR THE PREPARATION OF A THERAPEUTICAL COMPOSITION FOR TREATMENT OF VARIOUS DISEASES VEIJLEN N.V. (AN) 2005-05-06 WO claimed
EP-1476143-A1 COMPOSITIONS COMPRISING LYCOPENE FOR THE TREATMENT AND PREVENTION OF ANGIOGENESIS ASSOCIATED PATHOLOGIES DSM IP Assets B.V. (NL) 2004-11-17 EP claimed
WO-2004052351-A1 NOVEL USE OF LYCOPENE DSM IP ASSETS B.V. (CH) 2004-06-24 WO claimed
WO-2003068202-A1 COMPOSITIONS COMPRISING LYCOPENE FOR THE TREATMENT AND PREVENTION OF ANGIOGENESIS ASSOCIATED PATHOLOGIES DSM IP ASSETS B.V. (NL) 2003-08-21 WO claimed
US-20240115626-A1 COMPOSITIONS AND METHODS TO INCREASE PRODUCTION OF ISOTHIOCYANATES CHURCH & DWIGHT CO., INC. (US) 2024-04-11 US disclosed
US-4472304-A CARCINOSTATIC NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1984-09-18 US disclosed