Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942686 | 0.92 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL29086839 | 0.91 | TSHR (0.62) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10893415 | 0.91 | TSHR (0.71) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL521825 | 0.91 | TSHR (0.71) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL5844442 | 0.91 | TSHR (0.71) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27965774 | 0.91 | TSHR (0.71) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL35081 | 0.91 | TSHR (0.71) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7532090 | 0.91 | TSHR (0.71) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9319734 | 0.90 | TSHR (0.65) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7921491 | 0.88 | TSHR (0.67) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6171774-B1 | YELLOW IMAGE-FORMING EMULSION LAYER CONTAINS A YELLOW DYE-FORMING COUPLER AND AN ORGANIC SOLVENT-SOLUBLE POLYMER | KONICA CORPORATION (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0382443-A2 | A silver halide light-sensitive photographic material | KONICA CORPORATION (JP) | 1990-08-16 | — | — | EP | disclosed |