⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6054261 | 0.85 | ALDH1A1 (0.36) | — | |
| SCHEMBL7616955 | 0.84 | — | — | |
| SCHEMBL7616952 | 0.84 | — | — | |
| SCHEMBL736091 | 0.84 | — | — | |
| SCHEMBL8436447 | 0.82 | LCK (0.39) | — | |
| SCHEMBL8088176 | 0.80 | LCK (0.42) | — | |
| SCHEMBL2460259 | 0.78 | — | — | |
| SCHEMBL1651416 | 0.77 | — | — | |
| SCHEMBL28561755 | 0.76 | TSHR (0.38) | — | |
| SCHEMBL4968295 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200934-B | Compound containing benzomorpholone-biphenyl skeleton and preparation method and application thereof | 郑州大学 | 2022-05-31 | — | — | CN | claimed |
| CN-113200934-A | Compound containing benzomorpholone-biphenyl skeleton and preparation method and application thereof | 郑州大学 | 2021-08-03 | — | — | CN | claimed |
| JP-60142921-A | — | — | None | — | — | JP | disclosed |
| US-20260130893-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2026-05-14 | — | — | US | disclosed |
| EP-3938345-B1 | CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE | NOCION THERAPEUTICS INC (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-4737448-A1 | SARM1 ENZYME ACTIVITY INHIBITOR AND USE THEREOF | Artivila (ShenZhen) Innovation Center, Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2026089992-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| EP-4720038-A1 | (HETERO)ARYL-CARBONYL-HETEROBICYCLIC COMPOUNDS AS INHIBITORS OF PMS2 FOR CANCER AND DEGENERATIVE ILLNESSES | Neophore Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| EP-4698275-A1 | PYRROLIDINONE UREA FPR2 AGONISTS | Bristol-Myers Squibb Company (US) | 2026-02-25 | — | — | EP | disclosed |
| EP-4698516-A1 | PYRROLIDINONE UREA FPR2 AGONISTS | Bristol-Myers Squibb Company (US) | 2026-02-25 | — | — | EP | disclosed |
| US-20250388593-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2025-12-25 | — | — | US | disclosed |
| US-4892870-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, IMMUNOMODULATING AGENTS | BIOFOR, LTD. (US) | 1990-01-09 | — | — | US | disclosed |
| US-4833160-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | EISAI CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| US-4808713-A | Anthypertensive pyridazo [1,2-a][1,2]diazepines | HOFFMAN-LA ROCHE INC. (US) | 1989-02-28 | — | — | US | disclosed |
| US-4772701-A | Pyridazo[1,2]pyridazines and pyrazolo[1,2]pyridazines as antihypertensives | HOFFMANN-LA ROCHE INC. (US) | 1988-09-20 | — | — | US | disclosed |
| US-4658024-A | Pyrazolo [1,2-a][1,2]-diazepines useful as antihypertensives | HOFFMANN-LA ROCHE INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0204964-A1 | 2-Pyrrolidone derivatives, process for preparing them, pharmaceutical composition and use | Eisai Co., Ltd. (JP) | 1986-12-17 | — | — | EP | disclosed |
| JP-S60142921-A | ANTITUMOR AGENT | AJINOMOTO CO INC | 1985-07-29 | — | — | JP | disclosed |
| US-4512924-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1985-04-23 | — | — | US | disclosed |
| EP-0094095-A2 | Bicyclic carboxylic acids and their alkyl and aralkyl esters | F. HOFFMANN-LA ROCHE AG (CH) | 1983-11-16 | — | — | EP | disclosed |