Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.81 |
| ▸ | PPARG | P37231 | 7/20 | 0.81 |
| ▸ | PPARD | Q03181 | 7/20 | 0.81 |
| ▸ | PPARA | Q07869 | 7/20 | 0.81 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.81 |
| ▸ | TSHR | P16473 | 4/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.81 |
| ▸ | FABP4 | P15090 | 3/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | TLR2 | O60603 | 2/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.81 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.81 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | ESR1 | P03372 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL6373435 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL29182414 | 1.00 | GPR84 (0.81) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexanoate SCHEMBL28837892 | 0.98 | AKR1B1 (0.80) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL10595500 | 0.90 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexacosanoic Acid SCHEMBL25287701 | 0.90 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL25291604 | 0.90 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dotriacontanoic Acid SCHEMBL25298401 | 0.90 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL25288166 | 0.90 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL25281884 | 0.90 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL25286532 | 0.90 | GPR84 (1.00) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037136-A | Preparation method for magnesium stearate | NANTONG HAOYOU FOOD ADDITIVES CO LTD | 2015-11-11 | — | — | CN | claimed |
| CN-114865028-B | Method for adjusting hydrophobicity of integrated membrane electrode of fuel cell and application | 大连理工大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-114865028-A | Method for adjusting hydrophobicity of integrated membrane electrode of fuel cell and application | 大连理工大学 | 2022-08-05 | — | — | CN | disclosed |
| CN-105037136-A | Preparation method for magnesium stearate | NANTONG HAOYOU FOOD ADDITIVES CO LTD | 2015-11-11 | — | — | CN | disclosed |
| US-6184610-B1 | Electron-emitting device, electron source and image-forming apparatus | CANON KABUSHIKI KAISHA (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0757371-B1 | Electron-emitting device and electron source and image-forming apparatus using the same as well as method of manufacturing the same | CANON KK (JP) | 2000-10-25 | — | — | EP | disclosed |
| EP-0757371-A2 | Electron-emitting device and electron source and image-forming apparatus using the same as well as method of manufacturing the same | CANON KABUSHIKI KAISHA (JP) | 1997-02-05 | — | — | EP | disclosed |