Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | G6PD | P11413 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7891337 | 0.72 | HSD17B10 (0.36) | ESR1ESR2LMNAMEN1GAA | |
| SCHEMBL6464577 | 0.72 | HSD17B10 (0.36) | ESR1ESR2LMNAMEN1GAA | |
| SCHEMBL7885450 | 0.72 | LMNA (0.35) | ESR1ESR2LMNAMEN1GAA | |
| SCHEMBL7887023 | 0.71 | ESR1 (0.31) | ESR1ESR2LMNAMEN1GAA | |
| SCHEMBL6462493 | 0.70 | ESR1 (0.34) | ESR1ESR2LMNAMEN1GAA | |
| SCHEMBL13376700 | 0.68 | ESR1 (0.32) | ESR1ESR2LMNAMEN1GAA | |
| SCHEMBL7891306 | 0.68 | ESR1 (0.34) | ESR1ESR2LMNAMEN1GAA | |
| SCHEMBL6463142 | 0.68 | ESR1 (0.55) | ESR1ESR2LMNAMEN1GAA | |
| SCHEMBL7885452 | 0.67 | LMNA (0.34) | ESR1ESR2LMNAMEN1GAA | |
| SCHEMBL3381819 | 0.67 | CYP19A1 (0.48) | ESR1ESR2LMNAMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1163259-A1 | 14.BETA.,17-ALPHA-HYDROXYMETHYLANDROSTANE DERIVATIVES AS ANDROGENS | Akzo Nobel N.V. (NL) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000053619-A1 | 14.BETA., 17-ALPHA-HYDROXYMETHYLANDROSTANE DERIVATIVES AS ANDROGENS | AKZO NOBEL N.V. (NL) | 2000-09-14 | — | — | WO | disclosed |