Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 16/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2605283 | 0.83 | SLC6A9 (0.70) | SLC6A9SLC6A5LMNAHDAC4 | |
| SCHEMBL2605294 | 0.79 | SLC6A9 (0.68) | SLC6A9SLC6A5 | |
| SCHEMBL7892618 | 0.76 | SLC6A9 (0.57) | SLC6A9SLC6A5 | |
| SCHEMBL2605221 | 0.75 | SLC6A9 (0.80) | SLC6A9SLC6A5 | |
| SCHEMBL2605291 | 0.71 | SLC6A9 (0.85) | SLC6A9SLC6A5 | |
| SCHEMBL2605237 | 0.71 | SLC6A9 (0.78) | SLC6A9SLC6A5 | |
| SCHEMBL2605289 | 0.69 | SLC6A9 (0.68) | SLC6A9SLC6A5 | |
| SCHEMBL8083920 | 0.68 | SLC6A9 (0.64) | SLC6A9SLC6A5 | |
| SCHEMBL2605298 | 0.67 | SLC6A9 (0.66) | SLC6A9SLC6A5 | |
| SCHEMBL2126858 | 0.67 | SLC6A9 (0.86) | SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087762-A1 | 2-AZA-BICYCLO[2.2.1]HEPTANE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2010-08-05 | — | — | WO | disclosed |