Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888254 | 1.00 | CTSK (0.49) | CTSKCTSSPSENENCA1CA2 | |
| SCHEMBL3727156 | 0.92 | CTSK (0.52) | CTSKCTSSPSENENCA1CA2 | |
| SCHEMBL3727425 | 0.88 | CTSK (0.49) | CTSKCTSSPSENENCA1CA2 | |
| SCHEMBL21332574 | 0.87 | CTSK (0.50) | CTSKCTSSPSENENCA1CA2 | |
| SCHEMBL21332573 | 0.87 | CTSK (0.50) | CTSKCTSSPSENENCA1CA2 | |
| SCHEMBL16658566 | 0.84 | CTSK (0.54) | CTSKCTSSPSENENCA1CA2 | |
| SCHEMBL1515310 | 0.84 | CTSK (0.54) | CTSKCTSSPSENENCA1CA2 | |
| SCHEMBL13030924 | 0.84 | CTSK (0.48) | CTSKCTSSPSENENCA1CA2 | |
| SCHEMBL13030925 | 0.84 | CTSK (0.48) | CTSKCTSSPSENENCA1CA2 | |
| SCHEMBL8136020 | 0.83 | CTSK (0.48) | CTSKCTSSPSENENCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010103473-A1 | METHOD OF TREATMENT OF POLYCYSTIC DISEASES AND CHRONIC LYMPHOCYTIC LEUKEMIA | CHU DE BREST (FR) | 2010-09-16 | — | — | WO | disclosed |