Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | UMPS | P11172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866604 | 0.73 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL11826483 | 0.72 | UMPS (0.63) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL14041743 | 0.72 | PI4KA (0.38) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL29444520 | 0.72 | PI4KA (0.41) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL10183346 | 0.71 | PI4KA (0.36) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL10183384 | 0.70 | PI4KA (0.35) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL10183389 | 0.68 | PI4KA (0.36) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL11836106 | 0.67 | UMPS (0.45) | ALDH1A1LMNATDP1UMPS | |
| SCHEMBL7146147 | 0.67 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL10149282 | 0.66 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027359-A4 | MONOCYCLIC L-NUCLEOSIDES, ANALOGS AND USES THEREOF | ICN PHARMACEUTICALS (US) | 2001-07-25 | — | — | EP | disclosed |
| EP-1027359-A2 | MONOCYCLIC L-NUCLEOSIDES, ANALOGS AND USES THEREOF | ICN Pharmaceuticals, Inc. (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1998016186-A2 | MONOCYCLIC L-NUCLEOSIDES, ANALOGS AND USES THEREOF | ICN PHARMACEUTICALS, INC. (US) | 1998-04-23 | — | — | WO | disclosed |