Ethylene

Ethylene

SCHEMBL789398

C=C.O=C(O)c1ccc(C(=O)OC(OC(=O)c2ccc(C(=O)O)cc2)C2CCCCC2C(OC(=O)c2ccc(C(=O)O)cc2)OC(=O)c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.45
LMNA P02545 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
SCN1A P35498 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40
TP53 P04637 2/20 0.39
TSHR P16473 2/20 0.39
KMT2A Q03164 1/20 0.39
EPHX2 P34913 2/20 0.37
EPHX1 P07099 1/20 0.37
MAPT P10636 2/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
HCAR3 P49019 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL4958480 0.83 TSHR (0.41) SRD5A2LMNACYP1A2CYP2D6SCN1A
SCHEMBL3434702 0.82 LMNA (0.47) SRD5A2LMNACYP1A2CYP2D6SCN1A
SCHEMBL300467 0.80 TSHR (0.44) SRD5A2LMNATP53TSHRKMT2A
SCHEMBL23466843 0.79 LMNA (0.47) SRD5A2LMNACYP1A2CYP2D6SCN1A
SCHEMBL14677744 0.74 LMNA (0.52) SRD5A2LMNACYP1A2CYP2D6SCN1A
SCHEMBL31319176 0.70 STS (0.59) SRD5A2LMNASCN1ASCN2ASCN3A
SCHEMBL27467741 0.70 SERPINE1 (0.56) SRD5A2LMNATP53TSHRKMT2A
SCHEMBL23466842 0.70 CYP1A2 (0.48) LMNACYP1A2CYP2D6SCN1ASCN2A
Terephthalic Acid SCHEMBL19812471 0.70 TSHR (0.71) SRD5A2TP53TSHRSMN1; SMN2
Terephthalic Acid SCHEMBL16736991 0.70 TSHR (0.71) SRD5A2TP53TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012037180-A1 COEXTRUDED MULTILAYER FILM STRUCTURE DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-22 WO disclosed