Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789416 | 0.85 | APP (0.58) | APPNPSR1NPC1MAPTCYP1A2 | |
| SCHEMBL403663 | 0.80 | APP (0.73) | APPNPSR1NPC1MAPTCYP1A2 | |
| SCHEMBL30495998 | 0.80 | APP (0.73) | APPNPSR1NPC1MAPTCYP1A2 | |
| SCHEMBL17312253 | 0.80 | APP (0.73) | APPNPSR1NPC1MAPTCYP1A2 | |
| Benzene SCHEMBL28733255 | 0.80 | APP (0.73) | APPNPSR1NPC1MAPTCYP1A2 | |
| SCHEMBL9121457 | 0.77 | APP (0.69) | APPNPSR1NPC1MAPTCYP1A2 | |
| SCHEMBL15313378 | 0.75 | APP (0.58) | APPNPSR1NPC1MAPTCYP1A2 | |
| Biphenyl SCHEMBL1848421 | 0.72 | ALDH1A1 (0.53) | MAPTCYP1A2CYP3A4KDM4EALDH1A1 | |
| Diphenylacetylene SCHEMBL27339044 | 0.71 | APP (0.92) | APPNPC1MAPTCYP1A2CYP3A4 | |
| Benzene SCHEMBL346129 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11213800-B2 | Covalent organic framework films, and methods of making and uses of same | CORNELL UNIVERSITY (US) | 2022-01-04 | — | — | US | disclosed |
| US-20140037944-A1 | COVALENT ORGANIC FRAMEWORK FILMS, AND METHODS OF MAKING AND USES OF SAME | CORNELL UNIVERSITY (US) | 2014-02-06 | — | — | US | disclosed |
| WO-2012037090-A2 | COVALENT ORGANIC FRAMEWORK FILMS, AND METHODS OF MAKING AND USES OF SAME | CORNELL UNIVERSITY (US) | 2012-03-22 | — | — | WO | disclosed |