Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 3/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27492185 | 1.00 | YAP1 (0.47) | YAP1P2RX7KDM4EPKMCTSL | |
| SCHEMBL18788023 | 0.82 | YAP1 (0.60) | YAP1P2RX7KDM4EPKML3MBTL1 | |
| SCHEMBL20556236 | 0.82 | YAP1 (0.60) | YAP1P2RX7KDM4EPKML3MBTL1 | |
| SCHEMBL5569616 | 0.82 | YAP1 (0.55) | YAP1P2RX7KDM4EPKML3MBTL1 | |
| SCHEMBL12249924 | 0.81 | YAP1 (0.62) | YAP1P2RX7KDM4EPKML3MBTL1 | |
| SCHEMBL18822510 | 0.81 | YAP1 (0.62) | YAP1P2RX7KDM4EPKML3MBTL1 | |
| SCHEMBL12249929 | 0.79 | YAP1 (0.56) | YAP1P2RX7KDM4EPKML3MBTL1 | |
| SCHEMBL3008274 | 0.77 | YAP1 (0.60) | YAP1P2RX7KDM4EPKMCTSK | |
| SCHEMBL3008280 | 0.77 | YAP1 (0.60) | YAP1P2RX7KDM4EPKMCTSK | |
| SCHEMBL12652625 | 0.77 | YAP1 (0.60) | YAP1P2RX7KDM4EPKMCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218365-B1 | FOR TREATING OR PREVENTING A THROMBIN-RELATED DISEASE | AKZO NOBEL N.V. (NL) | 2001-04-17 | — | — | US | disclosed |
| CN-1212705-A | Serine protease inhibitors | AKZO NOBEL NV (NL) | 1999-03-31 | — | — | CN | disclosed |