Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22114789 | 0.85 | KMT2A (0.50) | KMT2AMEN1ALDH1A1HPGDNEU3 | |
| SCHEMBL7903346 | 0.83 | KLK1 (0.56) | KMT2AMEN1ALDH1A1HPGDNEU3 | |
| SCHEMBL30275453 | 0.82 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1HPGDNEU3 | |
| SCHEMBL3362895 | 0.82 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1HPGDNEU3 | |
| SCHEMBL3586872 | 0.81 | NEU3 (0.58) | KMT2AMEN1ALDH1A1HPGDNEU3 | |
| SCHEMBL27804334 | 0.78 | ALDH1A1 (0.64) | KMT2AMEN1ALDH1A1HPGDHDAC1 | |
| SCHEMBL17826361 | 0.77 | ESR1 (0.50) | KMT2AMEN1ALDH1A1HPGDESR1 | |
| SCHEMBL6105883 | 0.75 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1HPGDESR1 | |
| SCHEMBL30168176 | 0.75 | MAPT (0.63) | KMT2AMEN1ALDH1A1HPGDESR1 | |
| SCHEMBL28297474 | 0.75 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1HPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065717-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |