Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634390 | 0.83 | ALDH1A1 (0.74) | ALDH1A1CYP1A2TSHRHSD17B10GAA | |
| SCHEMBL38657948 | 0.83 | ALDH1A1 (0.74) | ALDH1A1CYP1A2TSHRHSD17B10GAA | |
| SCHEMBL29688451 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRHSD17B10POLB | |
| SCHEMBL1305446 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRHSD17B10POLB | |
| SCHEMBL5787232 | 0.80 | ALDH1A1 (0.50) | ALDH1A1CYP1A2TSHRHSD17B10GAA | |
| SCHEMBL16811748 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TSHRHSD17B10GAA | |
| SCHEMBL27474823 | 0.79 | ALDH1A1 (0.58) | ALDH1A1CYP1A2TSHRHSD17B10POLB | |
| SCHEMBL4361293 | 0.79 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRHSD17B10GAA | |
| SCHEMBL16310441 | 0.78 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRGAASMN1; SMN2 | |
| SCHEMBL2431836 | 0.78 | CYP1A2 (0.63) | ALDH1A1CYP1A2TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177360-B1 | Process for manufacture of integrated circuit device | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2001-01-23 | — | — | US | claimed |