Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12341004 | 1.00 | ZDHHC7 (0.59) | ZDHHC7ABCB1CA1CA2GPR84 | |
| SCHEMBL9427279 | 1.00 | ZDHHC7 (0.59) | ZDHHC7ABCB1CA1CA2GPR84 | |
| SCHEMBL93931 | 0.86 | GPR84 (0.48) | ZDHHC7ABCB1GPR84SPHK1FFAR1 | |
| SCHEMBL27812562 | 0.85 | ABCB1 (0.43) | ZDHHC7ABCB1CA1CA2MEN1 | |
| SCHEMBL25981301 | 0.85 | GPR84 (0.47) | ZDHHC7ABCB1GPR84SPHK1FFAR1 | |
| SCHEMBL12519182 | 0.84 | CA1 (0.45) | ZDHHC7ABCB1CA1CA2LMNA | |
| SCHEMBL12517987 | 0.84 | CA1 (0.45) | ZDHHC7ABCB1CA1CA2LMNA | |
| SCHEMBL10577082 | 0.83 | ZDHHC7 (0.58) | ZDHHC7ABCB1CA1CA2GPR84 | |
| SCHEMBL7253640 | 0.83 | ABCB1 (0.74) | ZDHHC7ABCB1CA1CA2GPR84 | |
| SCHEMBL10583618 | 0.83 | ZDHHC7 (0.58) | ZDHHC7ABCB1CA1CA2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001098329-A1 | POLYHYDROXY GLYCOPEPTIDE DERIVATIVES | THERAVANCE, INC. (US) | 2001-12-27 | — | — | WO | disclosed |