Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xylose SCHEMBL1513077 | 1.00 | LMNA (0.43) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Xylose SCHEMBL1513083 | 1.00 | LMNA (0.43) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Xylose SCHEMBL2319827 | 1.00 | LMNA (0.43) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Xylose SCHEMBL29287783 | 1.00 | LMNA (0.43) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Xylose SCHEMBL28231262 | 0.95 | PDE4A (0.46) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL23929880 | 0.93 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL344073 | 0.93 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Galactose SCHEMBL7895408 | 0.93 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL9453431 | 0.93 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AUSP2 | |
| Demannose SCHEMBL9123753 | 0.93 | LMNA (0.48) | LMNAL3MBTL1TDP1PDE4AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177409-B1 | 2-(ALKYL OR HALOALKYL)-3-HYDROXY PYRAN-4-ONE IS HYDROXYL-PROTECTED, AND REACTED WITH AN AMINO ITOL TO SUBSTITUTED THE INTRACYCLIC OXYGEN OF PYRANONE WITH THE AMINE OF THE AMINO ITOL; IRON(III) CHELATORS FOR BLOOD DISORDERS | INSTITUTO BIOCHIMICO PAVESE PHARMA S.P.A. (IT) | 2001-01-23 | — | — | US | disclosed |