Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16252085 | 1.00 | NR1H2 (0.48) | NR1H2MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL31554278 | 1.00 | NR1H2 (0.48) | NR1H2MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL12277546 | 1.00 | NR1H2 (0.48) | NR1H2MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL29928249 | 1.00 | NR1H2 (0.48) | NR1H2MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL17387946 | 1.00 | NR1H2 (0.48) | NR1H2MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL15890054 | 1.00 | NR1H2 (0.48) | NR1H2MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL25394396 | 0.90 | ALDH1A1 (0.46) | NR1H2MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL12615290 | 0.84 | ALDH1A1 (0.50) | NR1H2MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL1052491 | 0.84 | NR1H2 (0.50) | NR1H2MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL2930651 | 0.84 | NR1H2 (0.50) | NR1H2MEN1ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12448368-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| US-20250122176-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2025-04-17 | — | — | US | disclosed |
| US-20250092021-A9 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. | 2025-03-20 | — | — | US | disclosed |
| WO-2025039774-A1 | IMIDAZO[1,2-A]PYRIDINE TYPE IRAK DEGRADATION AGENT AND USE THEREOF | 泰诺瑞(天津)生物科技有限责任公司 | 2025-02-27 | — | — | WO | disclosed |
| CN-118955497-A | Imidazo [1,2-a ] pyridine IRAK4 degradation agent and application thereof | 泰诺瑞(天津)生物科技有限责任公司 | 2024-11-15 | — | — | CN | disclosed |
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2023-11-02 | — | — | US | disclosed |
| US-11667624-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| EP-4182320-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | Nido Biosciences, Inc. (US) | 2023-05-24 | — | — | EP | disclosed |
| US-20230049406-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. | 2023-02-16 | — | — | US | disclosed |
| WO-2022109551-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| US-8895602-B1 | 6-pyrazolylamido-3-substituted azabicyclo[3.1.0]hexane compounds as calcium channel inhibitors | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-11-25 | — | — | US | disclosed |
| US-8895602-B1 | 6-pyrazolylamido-3-substituted azabicyclo[3.1.0]hexane compounds as calcium channel inhibitors | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-11-25 | — | — | US | disclosed |
| US-20140343295-A1 | NOVEL 6-PYRAZOLYLAMIDO-3-SUBSTITUTED AZABICYCLO[3.1.0]HEXANE COMPOUNDS AS CALCIUM CHANNEL INHIBITORS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-11-20 | — | — | US | disclosed |
| US-20140343295-A1 | NOVEL 6-PYRAZOLYLAMIDO-3-SUBSTITUTED AZABICYCLO[3.1.0]HEXANE COMPOUNDS AS CALCIUM CHANNEL INHIBITORS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-11-20 | — | — | US | disclosed |
| US-8497289-B2 | 3.1.0 bicyclic GlyT1 inhibitors and methods of making and using same | VANDERBILT UNIVERSITY (US) | 2013-07-30 | — | — | US | disclosed |
| US-8497289-B2 | 3.1.0 bicyclic GlyT1 inhibitors and methods of making and using same | VANDERBILT UNIVERSITY (US) | 2013-07-30 | — | — | US | disclosed |
| US-8497289-B2 | 3.1.0 bicyclic GlyT1 inhibitors and methods of making and using same | VANDERBILT UNIVERSITY (US) | 2013-07-30 | — | — | US | disclosed |
| US-20100256192-A1 | 3.1.0 BICYCLIC GLYT1 INHIBITORS AND METHODS OF MAKING AND USING SAME | VANDERBILT UNIVERSITY | 2010-10-07 | — | — | US | disclosed |
| US-20100256192-A1 | 3.1.0 BICYCLIC GLYT1 INHIBITORS AND METHODS OF MAKING AND USING SAME | VANDERBILT UNIVERSITY | 2010-10-07 | — | — | US | disclosed |
| WO-2010078348-A1 | 3.1.0 BICYCLIC GLYT1 INHIBITORS AND METHODS OF MAKING AND USING SAME | VANDERBILT UNIVERSITY (US) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230049406-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | NR1H2 86/4885MEN1 2818/4885ALDH1A1 2325/4885 |
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | NR1H2 88/4885MEN1 2673/4885ALDH1A1 2260/4885 |
| US-20250122176-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | NR1H2 86/4885MEN1 2818/4885ALDH1A1 2325/4885 |
| US-11667624-B2 | Indole compounds as androgen receptor modulators | AR, FSHR, ADRB3 | NR1H2 134/4885MEN1 2646/4885ALDH1A1 2697/4885 |
| US-20250092021-A9 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | NR1H2 86/4885MEN1 2818/4885ALDH1A1 2325/4885 |
| US-20140343295-A1 | NOVEL 6-PYRAZOLYLAMIDO-3-SUBSTITUTED AZABICYCLO[3.1.0]HEXANE COMPOUNDS AS CALCIUM CHANNEL INHIBITORS | CACNA1B, CACNA1I, CACNA1D | NR1H2 3353/4885MEN1 1174/4885ALDH1A1 3014/4885 |
| US-12448368-B2 | Indole compounds as androgen receptor modulators | AR, FSHR, ADRB3 | NR1H2 134/4885MEN1 2646/4885ALDH1A1 2697/4885 |
| US-20100256192-A1 | 3.1.0 BICYCLIC GLYT1 INHIBITORS AND METHODS OF MAKING AND USING SAME | SLC7A1, SLC5A1, SLC1A1 | NR1H2 1255/4885MEN1 1213/4885ALDH1A1 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.