Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657236 | 0.91 | MAPT (0.49) | MAPTRAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL657237 | 0.91 | MAPT (0.49) | MAPTRAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL7892400 | 0.88 | MAPT (0.47) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL656896 | 0.80 | MAPT (0.50) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL7885636 | 0.79 | MAPT (0.47) | MAPTSMN1; SMN2MEN1KMT2AHSP90AA1 | |
| SCHEMBL655184 | 0.78 | MAPT (0.49) | MAPTRAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL655185 | 0.78 | MAPT (0.49) | MAPTRAB9ANPC1SMN1; SMN2NFKB1 | |
| SCHEMBL656955 | 0.74 | MAPT (0.52) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL28017989 | 0.74 | ALDH1A1 (0.51) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL7891959 | 0.72 | MAPT (0.41) | MAPTSMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010121963-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2010-10-28 | — | — | WO | disclosed |