Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.62 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | DNM2 | P50570 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903579 | 1.00 | DNM1 (0.62) | DNM1TSHRALDH1A1TDP1PLA2G1B | |
| SCHEMBL6036516 | 1.00 | DNM1 (0.62) | DNM1TSHRALDH1A1TDP1PLA2G1B | |
| SCHEMBL6549792 | 1.00 | DNM1 (0.62) | DNM1TSHRALDH1A1TDP1PLA2G1B | |
| SCHEMBL7904761 | 1.00 | DNM1 (0.62) | DNM1TSHRALDH1A1TDP1PLA2G1B | |
| SCHEMBL8508979 | 1.00 | DNM1 (0.62) | DNM1TSHRALDH1A1TDP1PLA2G1B | |
| SCHEMBL7902921 | 0.94 | DNM1 (0.60) | DNM1TSHRALDH1A1TDP1DNM2 | |
| SCHEMBL6036042 | 0.94 | DNM1 (0.60) | DNM1TSHRALDH1A1TDP1DNM2 | |
| SCHEMBL7184171 | 0.94 | DNM1 (0.60) | DNM1TSHRALDH1A1TDP1DNM2 | |
| SCHEMBL7903616 | 0.88 | TSHR (0.48) | DNM1TSHRALDH1A1TDP1PLA2G1B | |
| SCHEMBL7901425 | 0.88 | TSHR (0.48) | DNM1TSHRALDH1A1TDP1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1094801-A2 | POLY(DIALLYLAMINE)-BASED BILE ACID SEQUESTRANTS | GELTEX PHARMACEUTICALS, INC. (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-1999022743-A1 | POLY(DIALLYLAMINE)-BASED PHOSPHATE BINDERS | GELTEX PHARMACEUTICALS, INC. (US) | 1999-05-14 | — | — | WO | disclosed |
| WO-1998029107-A2 | POLY(DIALLYLAMINE)-BASED BILE ACID SEQUESTRANTS | GELTEX PHARMACEUTICALS, INC. (US) | 1998-07-09 | — | — | WO | disclosed |