Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.59 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PLEC | Q15149 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13807797 | 0.90 | CNR1 (0.64) | DRD2CNR1CNR2HRH4TP53 | |
| SCHEMBL7896371 | 0.90 | DRD2 (0.56) | DRD2CNR1CNR2HRH4TP53 | |
| SCHEMBL7904011 | 0.88 | DRD2 (0.64) | DRD2CNR1CNR2HRH4TP53 | |
| SCHEMBL7896379 | 0.85 | TP53 (0.64) | DRD2CNR1CNR2TP53NPSR1 | |
| SCHEMBL7902432 | 0.85 | DRD2 (0.59) | DRD2CNR1CNR2HRH4MEN1 | |
| SCHEMBL7902959 | 0.84 | CNR1 (0.58) | DRD2CNR1CNR2HRH4TP53 | |
| SCHEMBL7897128 | 0.83 | TP53 (0.66) | DRD2CNR1CNR2TP53NPSR1 | |
| SCHEMBL7899486 | 0.83 | NPSR1 (0.59) | DRD2CNR1CNR2TP53NPSR1 | |
| SCHEMBL7903134 | 0.83 | DRD2 (0.57) | DRD2CNR1CNR2TP53SMN1; SMN2 | |
| SCHEMBL7897794 | 0.83 | CNR1 (0.61) | DRD2CNR1CNR2TP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062565-A1 | MUSCARINIC AGONISTS | ACADIA PHARMACEUTICALS INC. (US) | 2010-06-03 | — | — | WO | disclosed |