Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789483 | 0.88 | PI4KA (0.51) | PI4KAPIK3CGKCNH2CA2CA9 | |
| SCHEMBL789603 | 0.81 | PIK3CG (0.66) | PI4KAPIK3CGMTOR | |
| SCHEMBL789602 | 0.78 | PI4KA (0.41) | PI4KAPIK3CGKCNH2CA2CA9 | |
| SCHEMBL789482 | 0.75 | PIK3CG (0.65) | PI4KAPIK3CGKCNH2MTOR | |
| SCHEMBL791064 | 0.75 | PIK3CG (0.81) | PI4KAPIK3CGMTOR | |
| SCHEMBL10277103 | 0.74 | PIK3CG (0.57) | PI4KAPIK3CGKCNH2BRD4MTOR | |
| SCHEMBL789481 | 0.72 | PI4KA (0.45) | PI4KAPIK3CGKCNH2CA2CA9 | |
| SCHEMBL10277220 | 0.70 | PIK3CG (0.78) | PI4KAPIK3CGMTOR | |
| SCHEMBL806968 | 0.70 | PIK3CG (0.72) | PI4KAPIK3CGMTOR | |
| SCHEMBL791171 | 0.69 | PIK3CG (0.54) | PI4KAPIK3CGKCNH2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |