Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | LIPC | P11150 | 3/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789481 | 0.89 | PI4KA (0.45) | PI4KAPIK3CGKCNH2JAK2JAK1 | |
| SCHEMBL789604 | 0.78 | PI4KA (0.46) | PI4KAPIK3CGKCNH2JAK2JAK1 | |
| SCHEMBL789603 | 0.77 | PIK3CG (0.66) | PI4KAPIK3CGMTOR | |
| SCHEMBL789483 | 0.72 | PI4KA (0.51) | PI4KAPIK3CGKCNH2JAK2JAK1 | |
| SCHEMBL789482 | 0.71 | PIK3CG (0.65) | PI4KAPIK3CGKCNH2MTOR | |
| SCHEMBL791169 | 0.71 | PIK3CG (0.47) | PI4KAPIK3CGKCNH2MTOR | |
| SCHEMBL10277103 | 0.70 | PIK3CG (0.57) | PI4KAPIK3CGKCNH2BRD4MTOR | |
| SCHEMBL791064 | 0.70 | PIK3CG (0.81) | PI4KAPIK3CGMTOR | |
| SCHEMBL790455 | 0.68 | PIK3CA (0.41) | PI4KAPIK3CGJAK2JAK1TYK2 | |
| SCHEMBL789984 | 0.68 | PI4KA (0.47) | PI4KAPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |