SCHEMBL7896096

SCHEMBL7896096

O=S(=O)(/C=C/c1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.75

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 13/20 0.61
PPARG P37231 3/20 0.58
MEN1 O00255 1/20 0.51
ALDH1A1 P00352 1/20 0.51
KMT2A Q03164 1/20 0.51
TLR9 Q9NR96 1/20 0.48
EGFR P00533 1/20 0.47
CYP1B1 Q16678 1/20 0.46
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7896098 1.00 NFE2L2 (0.61) NFE2L2PPARGMEN1ALDH1A1KMT2A
SCHEMBL1195311 0.93 NFE2L2 (0.57) NFE2L2PPARGTLR9EGFR
SCHEMBL1195313 0.93 NFE2L2 (0.57) NFE2L2PPARGTLR9EGFR
SCHEMBL1194466 0.90 NFE2L2 (0.61) NFE2L2ALDH1A1
SCHEMBL1194462 0.90 NFE2L2 (0.61) NFE2L2ALDH1A1
SCHEMBL5572462 0.86 TLR9 (0.64) NFE2L2PPARGALDH1A1KMT2ATLR9
SCHEMBL5572469 0.86 TLR9 (0.64) NFE2L2PPARGALDH1A1KMT2ATLR9
SCHEMBL29149692 0.86 TLR9 (0.64) NFE2L2PPARGALDH1A1KMT2ATLR9
SCHEMBL15497047 0.82 TLR9 (0.60) NFE2L2MEN1ALDH1A1KMT2ATLR9
SCHEMBL1194083 0.82 NFE2L2 (0.63) NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430125-B Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve 常州大学 2025-03-21 CN disclosed
CN-117430125-A Preparation method and application of manganese doped mesoporous structure-containing acidic Beta zeolite molecular sieve 常州大学 2024-01-23 CN disclosed
US-20210207175-A1 COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2021-07-08 US disclosed
CN-109096158-B Preparation method of (E) -alkenyl sulfone compound 石家庄学院 2020-06-12 CN disclosed
WO-2019238091-A1 COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF 中国科学院上海有机化学研究所 2019-12-19 WO disclosed
US-6201131-B1 REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210207175-A1 COMPOUND FOR REGULATING GENE EDITING EFFICIENCY AND APPLICATION THEREOF TET2, ZFX, ZFR NFE2L2 4073/4885PPARG 334/4885MEN1 3647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.