Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.66 |
| ▸ | PI4KA | P42356 | 7/20 | 0.66 |
| ▸ | MTOR | P42345 | 3/20 | 0.55 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790993 | 0.99 | PIK3CG (0.67) | PIK3CAPIK3CGPI4KAMTORPIK3R1 | |
| SCHEMBL806992 | 0.94 | PIK3CG (0.73) | PIK3CAPIK3CGPI4KAMTORPIK3R1 | |
| SCHEMBL807103 | 0.89 | PI4KA (0.76) | PIK3CAPIK3CGPI4KAMTOR | |
| SCHEMBL807088 | 0.86 | PIK3CG (0.82) | PIK3CAPIK3CGPI4KAMTORPIK3R1 | |
| SCHEMBL789854 | 0.85 | PI4KA (0.72) | PIK3CAPIK3CGPI4KAMTOR | |
| SCHEMBL10277402 | 0.85 | PI4KA (0.76) | PIK3CAPIK3CGPI4KAMTOR | |
| SCHEMBL807250 | 0.84 | PI4KA (0.76) | PIK3CAPIK3CGPI4KAMTOR | |
| SCHEMBL790456 | 0.83 | PIK3CA (0.46) | PIK3CAPIK3CGPI4KAMTORPIK3R1 | |
| SCHEMBL807176 | 0.83 | PIK3CG (0.87) | PIK3CAPIK3CGPI4KAMTORPIK3R1 | |
| SCHEMBL807195 | 0.83 | PI4KA (0.75) | PIK3CAPIK3CGPI4KAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |