Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8192864 | 0.95 | CHRM1 (0.58) | CHRM1 | |
| SCHEMBL8198388 | 0.92 | CHRM1 (0.49) | CHRM1IRAK4 | |
| Hydrochloric Acid SCHEMBL8192929 | 0.91 | CHRM1 (0.48) | CHRM1IRAK4 | |
| Hydrochloric Acid SCHEMBL8184166 | 0.85 | CHRM1 (0.41) | CHRM1IRAK4 | |
| SCHEMBL7885720 | 0.84 | CHRM1 (0.44) | CHRM1IRAK4 | |
| SCHEMBL8195607 | 0.83 | IRAK4 (0.36) | CHRM1IRAK4 | |
| SCHEMBL7892206 | 0.81 | CHRM1 (0.40) | CHRM1IRAK4 | |
| SCHEMBL8183398 | 0.79 | IRAK4 (0.35) | CHRM1IRAK4 | |
| SCHEMBL8196699 | 0.79 | CHRM1 (0.59) | CHRM1IRAK4 | |
| SCHEMBL8193429 | 0.79 | CHRM1 (0.57) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124312-A | ACTIVE DRUG FOR TREATING ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 2000-09-26 | — | — | US | claimed |
| EP-0900204-A4 | HETEROCYCLIC COMPOUNDS | LILLY CO ELI (US) | 2001-03-21 | — | — | EP | disclosed |
| US-6124312-A | ACTIVE DRUG FOR TREATING ALZHEIMER'S DISEASE | ELI LILLY AND COMPANY (US) | 2000-09-26 | — | — | US | disclosed |
| EP-0900204-A1 | HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040016-A1 | HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 1997-10-30 | — | — | WO | disclosed |