SCHEMBL8196699

SCHEMBL8196699

CCCCOc1nsnc1OC1CC2CC1CN2

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 7/20 0.59
IRAK4 Q9NWZ3 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8196276 0.92 CHRM1 (0.48) CHRM1IRAK4
Hydrochloric Acid SCHEMBL8196278 0.91 CHRM1 (0.47) CHRM1IRAK4
SCHEMBL8192229 0.82 CHRM1 (0.39) CHRM1IRAK4
SCHEMBL8183982 0.79 CHRM1 (0.56) CHRM1IRAK4
SCHEMBL7896872 0.79 CHRM1 (0.60) CHRM1IRAK4
SCHEMBL6988257 0.75 CHRM1 (0.59) CHRM1
SCHEMBL6912925 0.74 CHRM1 (1.00) CHRM1
SCHEMBL8192864 0.74 CHRM1 (0.58) CHRM1
SCHEMBL8076754 0.71 CHRM1 (0.85) CHRM1
SCHEMBL8505043 0.70 CHRM1 (0.58) CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6124312-A ACTIVE DRUG FOR TREATING ALZHEIMER'S DISEASE ELI LILLY AND COMPANY (US) 2000-09-26 US claimed
US-6124312-A ACTIVE DRUG FOR TREATING ALZHEIMER'S DISEASE ELI LILLY AND COMPANY (US) 2000-09-26 US disclosed