Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 7/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CD69 | Q07108 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896886 | 1.00 | PYGB (0.50) | PYGBCA1CA2CA9MAPK1 | |
| SCHEMBL29363859 | 1.00 | PYGB (0.50) | PYGBCA1CA2CA9MAPK1 | |
| SCHEMBL24997326 | 0.87 | MAPK1 (0.49) | PYGBCA1CA2CA9MAPK1 | |
| SCHEMBL16393092 | 0.86 | PYGB (0.53) | PYGBCA1CA2CA9MAPK1 | |
| SCHEMBL11439690 | 0.84 | PYGB (0.65) | PYGBCA1CA2CA9GAA | |
| SCHEMBL11439958 | 0.84 | PYGB (0.65) | PYGBCA1CA2CA9GAA | |
| SCHEMBL11435473 | 0.84 | PYGB (0.65) | PYGBCA1CA2CA9GAA | |
| SCHEMBL9126216 | 0.84 | PYGB (0.65) | PYGBCA1CA2CA9GAA | |
| SCHEMBL8817489 | 0.84 | PYGB (0.65) | PYGBCA1CA2CA9GAA | |
| SCHEMBL888575 | 0.84 | PYGB (0.65) | PYGBCA1CA2CA9GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187762-B1 | FUCOSIDE CONTAINING POLYMER | GELTEX PHARMACEUTICALS, INC. | 2001-02-13 | — | — | US | disclosed |
| US-5891862-A | VIRICIDES AND ACRYLAMIDE POLYMERS | GELTEX PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |