Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887316 | 1.00 | L3MBTL1 (0.46) | L3MBTL1KMT2ATSHRCA12CA9 | |
| SCHEMBL7897162 | 1.00 | L3MBTL1 (0.46) | L3MBTL1KMT2ATSHRCA12CA9 | |
| SCHEMBL7887311 | 1.00 | L3MBTL1 (0.46) | L3MBTL1KMT2ATSHRCA12CA9 | |
| SCHEMBL7887307 | 1.00 | L3MBTL1 (0.46) | L3MBTL1KMT2ATSHRCA12CA9 | |
| SCHEMBL31512221 | 0.92 | L3MBTL1 (0.44) | L3MBTL1KMT2ATSHRCA12CA9 | |
| SCHEMBL12544749 | 0.91 | L3MBTL1 (0.51) | L3MBTL1KMT2ATSHRCA12CA9 | |
| SCHEMBL2053503 | 0.91 | L3MBTL1 (0.51) | L3MBTL1KMT2ATSHRCA12CA9 | |
| SCHEMBL31512230 | 0.86 | L3MBTL1 (0.40) | L3MBTL1KMT2ATSHRCA12CA9 | |
| SCHEMBL7894554 | 0.80 | L3MBTL1 (0.45) | L3MBTL1KMT2ATSHRLMNAGAA | |
| SCHEMBL7894556 | 0.80 | L3MBTL1 (0.45) | L3MBTL1KMT2ATSHRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180611-B1 | INHIBITORS OF MATRIX METALLOPROTEINASES AND TUMOR NECROSIS FACTOR | DARWIN DISCOVERY, LTD. (GB) | 2001-01-30 | — | — | US | disclosed |
| US-5994312-A | Peptidyl compounds | DARWIN DISCOVERY, LTD. (GB) | 1999-11-30 | — | — | US | disclosed |