Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1595205 | 0.88 | AAK1 (0.44) | AAK1RAB9ANPC1EPHX2KMT2A | |
| SCHEMBL1595844 | 0.88 | AAK1 (0.44) | AAK1RAB9ANPC1EPHX2KMT2A | |
| SCHEMBL177958 | 0.84 | RAB9A (0.46) | AAK1RAB9ANPC1EPHX2KMT2A | |
| SCHEMBL178040 | 0.84 | RAB9A (0.46) | AAK1RAB9ANPC1EPHX2KMT2A | |
| SCHEMBL13127220 | 0.82 | — | — | |
| SCHEMBL1594478 | 0.81 | RAB9A (0.43) | AAK1RAB9ANPC1EPHX2KMT2A | |
| SCHEMBL1595365 | 0.81 | RAB9A (0.43) | AAK1RAB9ANPC1EPHX2KMT2A | |
| SCHEMBL178070 | 0.81 | RAB9A (0.46) | AAK1RAB9ANPC1EPHX2KMT2A | |
| SCHEMBL177757 | 0.81 | RAB9A (0.46) | AAK1RAB9ANPC1EPHX2KMT2A | |
| SCHEMBL1595876 | 0.79 | KDM4E (0.46) | RAB9ANPC1KMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118921-A1 | NOVEL P2X7R ANTAGONISTS AND THEIR USE | AFFECTIS PHARMACEUTICALS AG (DE) | 2010-10-21 | — | — | WO | disclosed |