Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 6/20 | 0.43 |
| ▸ | MMP3 | P08254 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897384 | 1.00 | F2 (0.56) | F2F10PRSS1MMP1MMP3 | |
| SCHEMBL4760675 | 0.93 | F2 (0.48) | F2F10PRSS1MMP1MMP3 | |
| SCHEMBL12525646 | 0.86 | MMP1 (0.55) | F2F10PRSS1MMP1MMP3 | |
| SCHEMBL12494289 | 0.86 | MMP1 (0.55) | F2F10PRSS1MMP1MMP3 | |
| SCHEMBL2707140 | 0.85 | F2 (0.59) | F2F10PRSS1MMP1MMP3 | |
| SCHEMBL203868 | 0.85 | F2 (0.59) | F2F10PRSS1MMP1MMP3 | |
| SCHEMBL13259958 | 0.85 | F2 (0.59) | F2F10PRSS1MMP1MMP3 | |
| SCHEMBL203869 | 0.85 | F2 (0.59) | F2F10PRSS1MMP1MMP3 | |
| SCHEMBL319693 | 0.85 | F2 (0.56) | F2F10PRSS1MMP1MMP3 | |
| SCHEMBL319691 | 0.85 | F2 (0.56) | F2F10PRSS1MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184207-B1 | A PEPTIDE INCLUDING SPECIFIED PIPERIDINE-CONTAINING GROUP, HAVING AN N-TERMINAL HYDROPHOBIC RESIDUE AND OPTIONALLY AN AMIDATED C-TERMINAL OF SPECIFIED END GROUPS; TREATING MULTIPLE SCLEROSIS OR RHEUMATOID ARTHRITIS | ZENECA LIMITED (GB) | 2001-02-06 | — | — | US | disclosed |