Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.62 |
| ▸ | TFEB | P19484 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897400 | 1.00 | KDM4E (0.65) | KDM4ENFE2L2TFEBMAPTNPC1 | |
| SCHEMBL9004163 | 0.79 | NFE2L2 (0.58) | KDM4ENFE2L2TFEBMAPTNPC1 | |
| SCHEMBL644527 | 0.79 | KDM4E (1.00) | KDM4ENFE2L2TFEBMAPTNPC1 | |
| SCHEMBL644526 | 0.79 | KDM4E (1.00) | KDM4ENFE2L2TFEBMAPTNPC1 | |
| SCHEMBL29372147 | 0.79 | KDM4E (1.00) | KDM4ENFE2L2TFEBMAPTNPC1 | |
| Coumarinic Acid Methyl Ether SCHEMBL28320175 | 0.77 | NFE2L2 (0.68) | KDM4ENFE2L2TFEBMAPTNPC1 | |
| SCHEMBL4019329 | 0.77 | NFE2L2 (0.79) | KDM4ENFE2L2TFEBMAPTNPC1 | |
| SCHEMBL1603719 | 0.77 | NFE2L2 (0.79) | KDM4ENFE2L2TFEBMAPTNPC1 | |
| SCHEMBL7915752 | 0.77 | NFE2L2 (0.79) | KDM4ENFE2L2TFEBMAPTNPC1 | |
| SCHEMBL16403662 | 0.77 | NFE2L2 (1.00) | KDM4ENFE2L2TFEBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177462-B1 | Unsaturated oxime ethers and their use as fungicides and insecticides | ROHM AND HAAS COMPANY | 2001-01-23 | — | — | US | disclosed |
| EP-0936213-A1 | Unsaturated oxime ethers and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 1999-08-18 | — | — | EP | disclosed |