Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896382 | 0.89 | KCNH2 (0.40) | PDE10ASLC6A3 | |
| SCHEMBL286576 | 0.75 | PDE10A (0.37) | MAOBALOX5APACHEPDE10ASLC6A3 | |
| SCHEMBL286634 | 0.71 | SCN9A (0.38) | MAOBALOX5APPDE10ASLC6A3PTGER4 | |
| SCHEMBL1420054 | 0.64 | DGAT1 (0.47) | PDE10ASLC6A3 | |
| SCHEMBL286596 | 0.63 | PDE10A (0.39) | ALOX5APPDE10ASLC6A3PTGER4 | |
| SCHEMBL298544 | 0.63 | PDE10A (0.48) | ALOX5APPDE10ASLC6A3HSD17B10 | |
| SCHEMBL13050095 | 0.61 | PDE10A (0.37) | PDE10ASLC6A3 | |
| SCHEMBL286616 | 0.60 | PTGER4 (0.39) | PDE10ASLC6A3PTGER4 | |
| SCHEMBL1424098 | 0.59 | PDE10A (0.62) | PDE10ASLC6A3 | |
| SCHEMBL23235776 | 0.59 | MAOB (0.59) | MAOBACHEPTGER4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128995-A1 | PHENOXYMETHYL HETEROCYCLIC COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2010-11-11 | — | — | WO | disclosed |