Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.70 |
| ▸ | PLG | P00747 | 1/20 | 0.62 |
| ▸ | PROC | P04070 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.62 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6638539 | 0.84 | F10 (0.68) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6638375 | 0.84 | F10 (0.88) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6641128 | 0.83 | F10 (0.67) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6642992 | 0.81 | F10 (0.64) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6664969 | 0.80 | F10 (0.88) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6644219 | 0.80 | F10 (0.88) | F10PLGPROCPRSS1RAD52 | |
| Trifluoroacetic Acid SCHEMBL7900413 | 0.79 | F10 (0.71) | F10PRSS1F2TMPRSS2KLK1 | |
| Trifluoroacetic Acid SCHEMBL6644883 | 0.78 | F10 (0.59) | F10PLGPROCPRSS1MLYCD | |
| SCHEMBL6643844 | 0.78 | F10 (0.66) | F10PLGPROCPRSS1 | |
| SCHEMBL14509265 | 0.77 | F10 (1.00) | F10PLGPROCPRSS1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323227-B1 | PRODRUGS | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-11-27 | — | — | US | claimed |
| US-6323227-B1 | PRODRUGS | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-11-27 | — | — | US | disclosed |