Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.67 |
| ▸ | PLG | P00747 | 1/20 | 0.64 |
| ▸ | PROC | P04070 | 1/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.59 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6664969 | 0.83 | F10 (0.88) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL7897485 | 0.83 | F10 (0.70) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6644219 | 0.82 | F10 (0.88) | F10PLGPROCPRSS1RAD52 | |
| Trifluoroacetic Acid SCHEMBL6638539 | 0.81 | F10 (0.68) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6638375 | 0.81 | F10 (0.88) | F10PLGPROCPRSS1F2 | |
| SCHEMBL13636886 | 0.81 | F10 (0.74) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6644490 | 0.80 | F10 (0.67) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6642992 | 0.79 | F10 (0.64) | F10PLGPROCPRSS1F2 | |
| SCHEMBL14509265 | 0.78 | F10 (1.00) | F10PLGPROCPRSS1F2 | |
| Trifluoroacetic Acid SCHEMBL6644883 | 0.77 | F10 (0.59) | F10PLGPROCPRSS1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931060-A4 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | AVENTIS PHARMA INC (US) | 2004-10-06 | — | — | EP | claimed |
| EP-0931060-A1 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-07-28 | — | — | EP | claimed |
| WO-1999000356-A1 | SUBSTITUTED N-[(AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1999-01-07 | — | — | WO | claimed |
| EP-0931060-A4 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | AVENTIS PHARMA INC (US) | 2004-10-06 | — | — | EP | disclosed |
| EP-0931060-A1 | SUBSTITUTED N- (AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) | 1999-07-28 | — | — | EP | disclosed |
| WO-1999000356-A1 | SUBSTITUTED N-[(AMINOIMINOMETHYL OR AMINOMETHYL)PHENYL]PROPYL AMIDES | RHÔNE-POULENC RORER PHARMACEUTICALS INC. (US) | 1999-01-07 | — | — | WO | disclosed |