Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.67 |
| ▸ | FNTB | P49356 | 17/20 | 0.67 |
| ▸ | ICMT | O60725 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906340 | 0.93 | FNTA (0.68) | FNTAFNTB | |
| SCHEMBL7906344 | 0.93 | FNTA (0.68) | FNTAFNTB | |
| Lithium SCHEMBL7906212 | 0.92 | FNTA (0.67) | FNTAFNTB | |
| SCHEMBL7906210 | 0.92 | FNTA (0.67) | FNTAFNTB | |
| Lithium Ion SCHEMBL7906208 | 0.92 | FNTA (0.68) | FNTAFNTB | |
| SCHEMBL7905427 | 0.88 | FNTA (0.74) | FNTAFNTBICMT | |
| SCHEMBL7905424 | 0.88 | FNTA (0.74) | FNTAFNTBICMT | |
| SCHEMBL7907033 | 0.87 | FNTA (0.73) | FNTAFNTBICMT | |
| SCHEMBL7907036 | 0.87 | FNTA (0.73) | FNTAFNTBICMT | |
| SCHEMBL7897710 | 0.87 | FNTA (0.62) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |