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Lithium

Lithium

SCHEMBL7906212

CCCOc1cccc(COCc2ccc(C(=O)N[C@@H](CCSC)C(=O)O)c(-c3ccccc3C)c2)c1.[Li]

nearest known ligand 0.67

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Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 9/20 0.67
▸ FNTB P49356 9/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7906340 0.99 FNTA (0.68) FNTAFNTB
SCHEMBL7906344 0.99 FNTA (0.68) FNTAFNTB
SCHEMBL7906210 0.98 FNTA (0.67) FNTAFNTB
SCHEMBL7897753 0.92 FNTA (0.67) FNTAFNTB
Lithium Ion SCHEMBL7906208 0.92 FNTA (0.68) FNTAFNTB
SCHEMBL7906319 0.90 FNTA (0.69) FNTAFNTB
SCHEMBL7906322 0.90 FNTA (0.69) FNTAFNTB
SCHEMBL7906575 0.89 FNTA (0.68) FNTAFNTB
SCHEMBL7906568 0.89 FNTA (0.68) FNTAFNTB
SCHEMBL7903903 0.88 FNTA (0.71) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204293-B1 INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH UNIVERSITY OF PITTSBURGH 2001-03-20 — — US disclosed