Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897520 | 0.91 | FFAR1 (0.44) | FFAR1PPARDSIRT2PARP10PARP15 | |
| SCHEMBL7903841 | 0.83 | FNTA (0.62) | — | |
| SCHEMBL7903839 | 0.83 | FNTA (0.62) | — | |
| SCHEMBL7904993 | 0.82 | KMT2A (0.46) | FFAR1PPARDFFAR4 | |
| SCHEMBL7904889 | 0.82 | FNTA (0.62) | — | |
| SCHEMBL7904896 | 0.82 | FNTA (0.62) | — | |
| SCHEMBL7897710 | 0.80 | FNTA (0.62) | — | |
| SCHEMBL7897713 | 0.80 | FNTA (0.62) | — | |
| Lithium Ion SCHEMBL7904893 | 0.80 | FNTA (0.63) | — | |
| SCHEMBL7897412 | 0.79 | FNTA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |