Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907180 | 0.90 | FNTA (0.41) | KMT2AFFAR1PPARDFFAR4PLA2G4B | |
| SCHEMBL7897863 | 0.82 | FFAR1 (0.47) | FFAR1PPARDFFAR4 | |
| SCHEMBL7904559 | 0.82 | MYC (0.43) | FFAR1FFAR4RAB9AFNTAFNTB | |
| SCHEMBL7906340 | 0.81 | FNTA (0.68) | FNTAFNTB | |
| SCHEMBL7906344 | 0.81 | FNTA (0.68) | FNTAFNTB | |
| SCHEMBL7905174 | 0.81 | PPARG (0.40) | FFAR1FFAR4RAB9AFNTAFNTB | |
| SCHEMBL7906210 | 0.80 | FNTA (0.67) | FNTAFNTB | |
| Lithium SCHEMBL7906212 | 0.80 | FNTA (0.67) | FNTAFNTB | |
| SCHEMBL7904826 | 0.79 | FNTA (0.42) | FFAR1FFAR4FNTAFNTBPPARG | |
| SCHEMBL7906995 | 0.79 | TDP1 (0.50) | FFAR1FFAR4RAB9AFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204293-B1 | INHIBITING POST-TRANSLATIONAL MODIFICATION OF THE ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE, PROTEIN GERANYLGERANYLTRANSFERASE, OR BOTH | UNIVERSITY OF PITTSBURGH | 2001-03-20 | — | — | US | disclosed |