Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.66 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.66 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.59 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 9/20 | 0.53 |
| ▸ | MAOA | P21397 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16312867 | 0.87 | PIK3CD (0.65) | PIK3CDPIK3CBALKHPGDKDM4E | |
| SCHEMBL592242 | 0.83 | PIK3CD (0.60) | PIK3CDPIK3CBALKHPGDKDM4E | |
| SCHEMBL12583468 | 0.81 | SLC16A3 (0.57) | SLC16A3HPGDKDM4EMAOBMAOA | |
| SCHEMBL21133105 | 0.81 | PIK3CD (0.65) | PIK3CDPIK3CBALKHPGDKDM4E | |
| SCHEMBL20445761 | 0.80 | PIK3CD (0.62) | PIK3CDPIK3CBALKHPGDKDM4E | |
| SCHEMBL3172696 | 0.80 | PIK3CD (0.67) | PIK3CDPIK3CBALKHPGDKDM4E | |
| SCHEMBL29524563 | 0.80 | PIK3CD (1.00) | PIK3CDPIK3CBALKHPGDKDM4E | |
| SCHEMBL29427470 | 0.80 | PIK3CD (1.00) | PIK3CDPIK3CBALKHPGDKDM4E | |
| SCHEMBL592311 | 0.80 | PIK3CD (1.00) | PIK3CDPIK3CBALKHPGDKDM4E | |
| SCHEMBL7898144 | 0.80 | KDM4E (0.62) | SLC16A3HPGDKDM4EMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207404-B1 | SUBJECTING THE CYTOCHROME P450 ENZYME AND THE COUMARIN BASED COMPOUND TO CONDITIONS WHEREBY THE CYTOCHROME P450 ENZYME CATALYZES THE CONVERSION OF THE COUMARIN BASED COMPOUND TO A FLUORESCENT PRODUCT | GENTEST CORPORATION | 2001-03-27 | — | — | US | disclosed |