Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 9/20 | 0.56 |
| ▸ | MAOA | P21397 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7910817 | 0.89 | SLC16A3 (0.56) | KDM4EHPGDNPC1MAPTALDH1A1 | |
| SCHEMBL7898123 | 0.80 | PIK3CD (0.66) | KDM4EHPGDNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL23835697 | 0.79 | KDM4E (0.60) | KDM4EHPGDNPC1MAPTALDH1A1 | |
| SCHEMBL9149718 | 0.79 | KDM4E (0.63) | KDM4EHPGDNPC1MAPTALDH1A1 | |
| SCHEMBL381288 | 0.79 | KDM4E (0.67) | KDM4EHPGDNPC1MAPTALDH1A1 | |
| SCHEMBL2490607 | 0.78 | KDM4E (0.74) | KDM4EHPGDNPC1MAPTALDH1A1 | |
| SCHEMBL3086292 | 0.78 | KDM4E (1.00) | KDM4EHPGDNPC1MAPTALDH1A1 | |
| SCHEMBL12583468 | 0.77 | SLC16A3 (0.57) | KDM4EHPGDNPC1MAPTALDH1A1 | |
| SCHEMBL93260 | 0.76 | SLC16A3 (1.00) | NPC1SLC16A3MAOBMAOAMEN1 | |
| SCHEMBL16674817 | 0.76 | KDM4E (0.59) | KDM4EHPGDNPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207404-B1 | SUBJECTING THE CYTOCHROME P450 ENZYME AND THE COUMARIN BASED COMPOUND TO CONDITIONS WHEREBY THE CYTOCHROME P450 ENZYME CATALYZES THE CONVERSION OF THE COUMARIN BASED COMPOUND TO A FLUORESCENT PRODUCT | GENTEST CORPORATION | 2001-03-27 | — | — | US | disclosed |