Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7907737 | 0.99 | EGFR (0.44) | EGFRERBB2SLC29A1ADORA3SMN1; SMN2 | |
| SCHEMBL342030 | 0.99 | EGFR (0.46) | EGFRERBB2SLC29A1ADORA3SMN1; SMN2 | |
| SCHEMBL9447631 | 0.99 | EGFR (0.46) | EGFRERBB2SLC29A1ADORA3SMN1; SMN2 | |
| SCHEMBL3067 | 0.99 | EGFR (0.46) | EGFRERBB2SLC29A1ADORA3SMN1; SMN2 | |
| SCHEMBL30998177 | 0.99 | EGFR (0.46) | EGFRERBB2SLC29A1ADORA3SMN1; SMN2 | |
| SCHEMBL969339 | 0.99 | EGFR (0.46) | EGFRERBB2SLC29A1ADORA3SMN1; SMN2 | |
| Water SCHEMBL8705007 | 0.98 | EGFR (0.45) | EGFRERBB2SLC29A1ADORA3SMN1; SMN2 | |
| Water SCHEMBL8705010 | 0.98 | EGFR (0.45) | EGFRERBB2SLC29A1ADORA3SMN1; SMN2 | |
| Water SCHEMBL27310451 | 0.98 | EGFR (0.45) | EGFRERBB2SLC29A1ADORA3SMN1; SMN2 | |
| SCHEMBL7898163 | 0.98 | EGFR (0.45) | EGFRERBB2SLC29A1ADORA3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207650-B1 | USEFUL AS INTERMEDIATES OR AS ANTIVIRAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 2001-03-27 | — | — | US | disclosed |
| EP-0398230-B1 | Antiviral, highly water soluble, stable, crystalline salts of 2',3'-dideoxyinoside monohydrate, 2',3'-dideoxy-2',3'-didehydrothymidine monohydrate and 2',3'-dideoxy-2'-fluoroinosine hemihydrate | BRISTOL MYERS SQUIBB CO (US) | 1998-01-21 | — | — | EP | disclosed |