SCHEMBL342030

SCHEMBL342030

OC[C@@H]1C[C@@H](F)[C@H](n2cnc3c(O)ncnc32)O1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.46
ERBB2 P04626 1/20 0.46
SLC29A1 Q99808 3/20 0.43
ADORA3 P0DMS8 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
ADORA1 P30542 2/20 0.43
DPP4 P27487 1/20 0.43
MEN1 O00255 1/20 0.43
SLC28A1 O00337 1/20 0.43
MAP3K7 O43318 1/20 0.43
SLC28A2 O43868 1/20 0.43
GAPDH P04406 1/20 0.43
MAPK1 P28482 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA2B P29275 1/20 0.43
STAT6 P42226 1/20 0.43
PI4KA P42356 1/20 0.43
KMT2A Q03164 1/20 0.43
PI4K2B Q8TCG2 1/20 0.43
DOT1L Q8TEK3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3067 1.00 EGFR (0.46) EGFRERBB2SLC29A1ADORA3SMN1; SMN2
SCHEMBL969339 1.00 EGFR (0.46) EGFRERBB2SLC29A1ADORA3SMN1; SMN2
SCHEMBL9447631 1.00 EGFR (0.46) EGFRERBB2SLC29A1ADORA3SMN1; SMN2
SCHEMBL30998177 1.00 EGFR (0.46) EGFRERBB2SLC29A1ADORA3SMN1; SMN2
SCHEMBL7898159 0.99 EGFR (0.45) EGFRERBB2SLC29A1ADORA3SMN1; SMN2
Water SCHEMBL8705007 0.99 EGFR (0.45) EGFRERBB2SLC29A1ADORA3SMN1; SMN2
Water SCHEMBL27310451 0.99 EGFR (0.45) EGFRERBB2SLC29A1ADORA3SMN1; SMN2
SCHEMBL7898163 0.99 EGFR (0.45) EGFRERBB2SLC29A1ADORA3SMN1; SMN2
Water SCHEMBL8705010 0.99 EGFR (0.45) EGFRERBB2SLC29A1ADORA3SMN1; SMN2
Water SCHEMBL7907737 0.98 EGFR (0.44) EGFRERBB2SLC29A1ADORA3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741372-B2 Guanylhydrazones useful for treating diseases associated with T cell activation CYTOKINE PHARMASCIENCES, INC. (US) 2010-06-22 US claimed
US-20100080830-A1 SYSTEMIC DELIVERY OF ANTIVIRAL AGENTS PSIVIDA INC. (US) 2010-04-01 US claimed
US-20060154892-A1 Procedure to block the replication of reverse transcriptase dependent viruses by the use of inhibitors of deoxynucleotides synthesis LORI FRANCO 2006-07-13 US claimed
US-20040115268-A1 Systemic delivery of antiviral agents CONTROL DELIVERY SYSTEMS, INC. 2004-06-17 US claimed
WO-2004043435-A2 SYSTEMIC DELIVERY OF ANTIVIRAL AGENTS CONTROL DELIVERY SYSTEMS, INC. (US) 2004-05-27 WO claimed
US-6207650-B1 USEFUL AS INTERMEDIATES OR AS ANTIVIRAL AGENTS BRISTOL-MYERS SQUIBB COMPANY 2001-03-27 US claimed
US-6194390-B1 ADMINISTERING HYDROXYUREA AND A 2'-FLUOROPURINE-DIDEOXY-NUCLEOSIDE SELECTED FROM THE GROUP OF 2'-FLUORO-2',3'-DIDE-OXYADENOSINE,-DIDEOXYINOSINE, AND -DIDEOXYGUANOSINE WITH A CARRIER OR EXCIPIENT; VIRICIDES; RETROVIRUSES; PLANT VIRUSES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES 2001-02-27 US claimed
EP-0398230-B1 Antiviral, highly water soluble, stable, crystalline salts of 2',3'-dideoxyinoside monohydrate, 2',3'-dideoxy-2',3'-didehydrothymidine monohydrate and 2',3'-dideoxy-2'-fluoroinosine hemihydrate BRISTOL MYERS SQUIBB CO (US) 1998-01-21 EP claimed
EP-0464137-A4 INHIBITION OF HIV USING SYNERGISTIC COMBINATIONS OF NUCLEOSIDE DERIVATIVES 1992-01-15 EP claimed
EP-0464137-A1 INHIBITION OF HIV USING SYNERGISTIC COMBINATIONS OF NUCLEOSIDE DERIVATIVES ONCOGEN LIMITED PARTNERSHIP (US) 1992-01-08 EP claimed
EP-0398230-A2 Antiviral, highly water soluble, stable, crystalline salts of 2',3'-dideoxyinoside monohydrate, 2',3'-dideoxy-2',3'-didehydrothymidine monohydrate and 2',3'-dideoxy-2'-fluoroinosine hemihydrate Bristol-Myers Squibb Company (US) 1990-11-22 EP claimed
WO-1990011081-A1 INHIBITION OF HIV USING SYNERGISTIC COMBINATIONS OF NUCLEOSIDE DERIVATIVES ONCOGEN LIMITED PARTNERSHIP (US) 1990-10-04 WO claimed
JP-3005477-A None JP disclosed
US-20250313905-A1 METHODS AND COMPOSITIONS FOR IMPROVED PSYCHOLOGICAL AND RESILIENCE MEASURES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-10-09 US disclosed
US-12404304-B1 Telomerase reverse transcriptase (TERT) expression enhancing compounds and methods for using the same SIERRA SCIENCES, LLC (US) 2025-09-02 US disclosed
US-12364717-B2 Compositions and methods for inhibiting seizures THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-22 US disclosed
JP-H035477-A ANTIVIRAL, HIGHLY WATER SOLUBLE, STABLE, CRYSTALLINE SALTS OF 2',3'-DIDEOXYINOSINE MONOHYDRATE, 2',3'-DIDEOXY-2',3'-DIDEHYDROTHYMIDINE MONOHYDRATE AND 2',3'-DIDEOXY-2'-FLUOROINOSINE HEMIHYDRATE BRISTOL MYERS SQUIBB CO 1991-01-11 JP disclosed
EP-0398230-A2 Antiviral, highly water soluble, stable, crystalline salts of 2',3'-dideoxyinoside monohydrate, 2',3'-dideoxy-2',3'-didehydrothymidine monohydrate and 2',3'-dideoxy-2'-fluoroinosine hemihydrate Bristol-Myers Squibb Company (US) 1990-11-22 EP disclosed
EP-0398230-A2 Antiviral, highly water soluble, stable, crystalline salts of 2',3'-dideoxyinoside monohydrate, 2',3'-dideoxy-2',3'-didehydrothymidine monohydrate and 2',3'-dideoxy-2'-fluoroinosine hemihydrate Bristol-Myers Squibb Company (US) 1990-11-22 EP disclosed
WO-1990011081-A1 INHIBITION OF HIV USING SYNERGISTIC COMBINATIONS OF NUCLEOSIDE DERIVATIVES ONCOGEN LIMITED PARTNERSHIP (US) 1990-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100080830-A1 SYSTEMIC DELIVERY OF ANTIVIRAL AGENTS HAVCR2, MAVS, PGF EGFR 3385/4885ERBB2 3602/4885SLC29A1 10/4885
US-12404304-B1 Telomerase reverse transcriptase (TERT) expression enhancing compounds and methods for using the same TERT, TELO2, POT1 EGFR 2775/4885ERBB2 2690/4885SLC29A1 2352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.